So it may be hard for you to tell if sexual side effects are caused by Topamax itself or by certain mood changes the drug may cause. Some side effects can cause long-term effects if they arent treated, such as increased pressure in your eye. Does metabolism change or just taste for foods/amts? Apparently it does make soda taste weird!!!!!!!!!!! After a while it turned into simple forgetfulness. Taste . Tell your doctor if you have lung problems before starting Topamax. And this could increase your risk for having a high level of acid as a side effect of Topamax. Examples include hair loss and eye problems. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. And all food tasted weird, exept for garlic for some reason. This can help you make informed decisions about the treatments you take during pregnancy. If they do decide to prescribe Topamax, they may start you with a lower dose than usual. That tingle feeling and digestion issues are super common with topomax withdraw. If this condition isnt treated, it can lead to osteoporosis. The pain can be so severe that it becomes debilitating. Although research is ongoing, CBD is currently approved to treat seizures caused by two rare forms of epilepsy and tuberous sclerosis complex. For more information, please see our (The average amount of weight lost in these studies wasnt noted.). We avoid using tertiary references. During your Topamax treatment, consider keeping notes on any side effects youre having. If you have more questions about liver problems with Topamax, your doctor can help. Its possible. This lessens your risk of seizures after stopping Topamax. ? A meta-analytic comparison of topiramate-related adverse drug reactions in epilepsy and migraine. If youd like to notify the FDA about a side effect youve had with Topamax, visit MedWatch. Hair loss from Topamax is generally reversible. Uses. Dysgeusia is a taste disorder. If you have kidney problems, such as chronic kidney disease, you have an increased risk of both metabolic acidosis and kidney stones as a complication. Keep reading to learn about the common, mild, and serious side effects of Topamax and ways to deal with them. Educational text answers on HealthTap are not intended for individual diagnosis, treatment or prescription. loss is a common (usually desired) side effect from med, can cause strange sensations, sometimes you have to decrease dose or increase more slowly, but if not intolerable, would try to stick it out at least 2 weeks and symptoms generally resolve. Oxford University Press is a department of the University of Oxford. American Society of Health-System Pharmacists 2020. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If youre pregnant or planning a pregnancy, talk with your doctor before starting Topamax. Carbonation dysgeusia after topiramate initiation has been reported by patients taking the medication but is not well identified in the literature. "Local trauma" to the tastebuds aka burning your tongue on hot stuff can change your sense of taste. Oh, yeah. All rights reserved. Below are a few of the more common side effects reported by people who took Topamax in studies. Your side effect notes can include things such as: Keeping notes and sharing them with your doctor will help your doctor learn more about how Topamax affects you. After you stop taking Topamax, the symptoms you were taking it for may return. Obstetric clinical pharmacy: A necessary birth of a new specialty, Sister Mary Louise Degenhart dies at 85 years, Infection risk and management strategies for patients with cirrhosis taking proton pump inhibitors, Cold chain experts look to future during latest ASHP forum, National trends in prescription drug expenditures and projections for 2023, ASHP National Surveys of Pharmacy Practice in Hospital Settings, Population Health Management Theme Issues, Practice Advancement Initiative Collection, Transitions of Care/Medication Reconciliation, Emergency Preparedness and Clinician Well-being, Author Instructions for Residents Edition, https://www.aan.com/siteassets/home-page/tools-and-resources/academic-neurologist--researchers/program-director-tools/16tasteandsmell_tr.pdf, https://www.pharmacytimes.com/publications/issue/2015/July2015/Drug-Induced-Metallic-Taste-No-Irony, https://www.aafp.org/afp/2000/0115/p427.html#afp20000115p427-t2, https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020844s041lbl.pdf, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724372/, https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model, Receive exclusive offers and updates from Oxford Academic, Copyright 2023 American Society of Health-System Pharmacists. The term carbonation dysgeusia is used to describe distortions of carbonation taste quality leading to diminished or complete elimination of the pungency or prickly sensation experienced on imbibing carbonated beverages.8 Other cases of topiramate-induced carbonation dysgeusia have been widely mentioned in various Internet patient forums.9,10 Although topiramate-induced dysgeusia has been reported in numerous randomized controlled trials, most of the trial reports did not define the specific manifestation of dysgeusia.11-13 Furthermore, our PubMed search, conducted without date limits using the terms topiramate and carbonation dysgeusia or drug-induced taste perversion, identified no previous reports describing this reaction in detail. This could raise your risk for having a high level of acid as a side effect of Topamax. ! They may also recommend that you visit an eye doctor. Call 911 or the local emergency number, or text TALK to 741741 to communicate with a trained crisis counselor. Most of the participants did lose weight while on the drug, significantly more than the placebo group, however, the side effects discouraged some from continuing the trial. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. Topamax (topiramate) is a prescription drug thats used to treat epilepsy and help prevent migraine headaches. I also just stopped sweating. If you have weight loss while taking the drug, its possible you could gain weight after you stop taking Topamax. If youd like to learn more about Topamax, talk with your doctor or pharmacist. They can help answer any questions you have about side effects from taking the drug. If the side effects seem life threatening or if you think youre having a medical emergency, immediately call 911 or your local emergency number. I'm on it for migraines. Your doctor can help determine whether treatment with Topamax is safe for you. She was also experiencing mild hand and feet paresthesia, which are commonly reported adverse effects of the medication.14 Bloodwork performed 10 months after topiramate initiation indicated that all values were within normal limits, with the exception of a low alkaline phosphatase (ALP) level (38 U/L [reference range, 50-136 U/L] and low creatinine concentration (0.7 mg/dL [reference range, 0.8-1.3 mg/dL]; neither low value was deemed concerning. BMD describes how strong the bones are. Promptly after the initiation of topiramate, the patient lost her ability to taste carbonation in all beverages, including soda, seltzer, and beer. .it is the topamax. Topamax (topiramate) tablets, for oral use; Topamax (topiramate capsules) sprinkle capsules, for oral use. Joeyshoney bleeding. Talk with your doctor to learn if Topamax is right for you. Although rare, Topamax can also cause a glaucoma attack. It is just as hard coming off this drug as it is going on it. You may need blood tests to make sure the level of acid in your blood is safe. chronic obstructive pulmonary disease (COPD), accessdata.fda.gov/drugsatfda_docs/label/2021/020505s063,020844s054lbl.pdf, Getting Relief from Migraines: Preventive and Acute Treatments, Seizure First Aid: How to Respond When Someone Has an Episode. Be sure to talk with your doctor about your health history before you take Topamax. You may have mild side effects from Topamax. what were you taking it for if you don't mind me asking? The taste of food/drink however will remain the same the entire time you are on Topamax no matter what the dose. This side effect wasnt common in clinical trials and was only reported by people taking the drug for epilepsy. Or you may notice a metallic or unusual taste in your mouth. Liver problems could raise your risk for a high level of ammonia in your blood, which is a possible side effect of Topamax. inflammation of the tissue lining the sinuses. If you develop a side effect while taking Topamax and want to tell the FDA about it, visit MedWatch. They can recommend ways to reach or maintain a weight thats healthy for you. Topamax is used to treat certain types of epilepsy in children ages 2 years and older, and to prevent migraine headaches in children ages 12 years and older. And do not stop using Topamax unless your doctor recommends it. They will help keep your hair in great shape and keep it on your head. Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Maria Charbonneau, PharmD, Courtney Doyle-Campbell, PharmD, AHSCP-CHC, Corey Laskey, PharmD, BCPP, Kam Capoccia, PharmD, BCPS, CDE, Carbonation dysgeusia associated with topiramate, American Journal of Health-System Pharmacy, Volume 77, Issue 14, 15 July 2020, Pages 11131116, https://doi.org/10.1093/ajhp/zxaa123. A throbbing headache can occur due to migraine, tension, or neuralgia. Connect with a U.S. board-certified doctor by text or video anytime, anywhere. But again, it sounds like over 50% of people take topomax with great results. To enroll in the North American Antiepileptic Drug Pregnancy Registry, visit the registrys site. Topamax can cause a high level of acid in the blood. Oh Yes.. Topamax made me stupid and crave non fat milk like it was the best thing in the world. Allergic reaction. A bitter or bad taste in the mouth can occur after eating pungent or sour foods, but it can also stem from hormonal changes, poor oral health, medication use, stress, and many other factors. If your symptoms seem life threatening, call 911 or your local emergency number immediately. I just started on Topamax (topiramate), (topiramate) but I've gotten a headache today that doesn't seem to want to go away. . You can also see Topamaxs prescribing information or talk with your doctor or pharmacist. Theyre also more likely to be born small for their gestational age. Serious side effects that have been reported with Topamax include: If you develop serious side effects while taking Topamax, call your doctor right away. Ask your doctor what other medications are better options for you. Depression or suicidal thoughts. If you have questions about possible long-term side effects of Topamax, talk with your doctor or pharmacist. Many are mild and tend to go away on their own after a few days or weeks. How should I manage side effects I may have from Topamax. Scientists use genetic rewiring to increase lifespan of cells, Beyond amyloid and tau: New targets in developing dementia treatments, Napping longer than 30 minutes linked to higher risk of obesity and high blood pressure, Activity 'snacks' could lower blood sugar, complication risk in type 1 diabetes, Trokendi XR side effects: What you should know, feelings of burning or numbness in your hands and feet, producing less sweat than usual, especially in hot weather. A high temperature for children ages 2 years and older is above 99.5F (37.5C). In addition, weight and height may be affected in children taking Topamax. Most side effects tend to go away soon after you start or stop taking the drug. I've been on Topamax for two months and I still can't stand to smell food, or taste what I eat or drink. It may not be safe to use Topamax while breastfeeding. and our Your doctor can help determine whether treatment with Topamax is safe for you. Changes in taste was a common side effect reported by people who took Topamax for preventing migraine headaches in clinical trials. At that time (and also during the initiation and titration of topiramate), the patient was not taking any other medications, vitamins, or supplements. Topamax can increase your risk of depression and suicidal thoughts or actions. While treatment plans must be individualized for each person, with careful consideration of anticipated results, the benefits of treatment with topiramate likely outweigh the risks for many patients. Like other drugs, Topamax can cause side effects. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. Youll get first-hand stories from people living with this condition as well as tips for managing symptoms. Through sensory nerves, the receptors communicate information about tastes to the brain. The 988 Suicide and Crisis Lifeline is available 24 hours a day at 988. This should cause side effects of the drug to go away. Side effects in clinical trials were slightly different depending on whether people used the drug to treat seizures or to prevent migraine headaches. Post discussions, articles, and questions about uses, side effects, experiences, and any advances that may happen with this drug. More common side effects in people taking Topamax for migraine include: More common side effects in people taking Topamax for epilepsy include: Read on to learn about other mild and severe side effects that can happen with Topamax. You should avoid these activities until you know how Topamax affects you. Click here for more links and local resources. Although rare, treatment with Topamax can cause a condition called secondary closed-angle glaucoma. In clinical trials, how often certain side effects occurred varied depending on which dose of Topamax was taken. Treatment with Topamax can cause a variety of cognitive side effects. Your doctor can recommend whether Topamax is safe for you to take. Symptoms can be mild or serious and can include: For mild symptoms of an allergic reaction, call your doctor right away. Topiramate ( Qudexy XR, Topamax, Trokendi XR) Valproic acid If the drugs don't work, you might have surgery to remove the damaged sensory receptors (olfactory mucosa) in your nasal cavity. But these side effects werent common in studies of the drug. (2022). The patient looked to online forums for patients with epilepsy and migraine for information on the phenomenon and found numerous reports of similar experiences from others taking topiramate on the websites epilepsy.org and migraine.org.9,10 In one such forum, someone suggested using a straw to help mitigate the adverse effect, and our patient found the suggestion helpful. What are the more common side effects of Topamax? They may recommend a different drug for your condition. For more information, you can refer to Topamaxs prescribing information. Topamax doesnt rely heavily on your liver to help remove it from your body. The Topamax sprinkle capsule or Qudexy XR extended-release capsule may be swallowed whole or opened and sprinkled on a small amount (1 teaspoon) of soft food (eg, applesauce). The first beverage she tried following initiation of topiramate 25 mg by mouth twice daily was cold seltzer water from a can, and she immediately noted a flat taste. In fact, carbonic anhydrase 4 may function as the principle CO2 taste sensor for the human body. I also lost all interest in food, no apetite, had no energy to cook it, and just threw it up if I did eat it. Drinking alcohol while taking Topamax can increase your risk of certain side effects and increase the chance that theyll be serious. These symptoms could be life threatening and require immediate medical care. If you have side effects that wont go away or are hard to deal with, your doctor will likely have you wean off Topamax. Although topiramate has multiple mechanisms of action, its carbonic anhydrase inhibitory effects are similar to those of acetazolamide.17. If you are not in the same household, stay on the phone with them until help arrives. * To learn more about this side effect, see the Side effects explained section below. Mouths are sensitive to the effects of carbon dioxide, the substance that initiates the chemical pathway eliciting a fizzy and tingling sensation upon consumption of carbonated beverages.19 Results from Dunkel and Hofmanns18 study suggested that CO2 acts on the sour taste system as well as somatosensory pathways; the fizzy and tingling perception of carbonated beverages is likely due to gustatory and somatosensory inputs leading to multimodal sensation. Question posted by sallymaebooth on 22 April 2013, Last updated on 22 November 2016 by ltwilliams72, I've read on the side effects that agitation is a possible side effect - I've only been taking topamax for a week now. But severe side effects that could lead to long-term problems and permanent damage from Topamax are possible. It's not common but it can happen and did to me. However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. Taste buds are each made up of taste receptor cells that bind to small molecules related to flavor. Can diet help improve depression symptoms? I take 500mcg a day. Carbonation dysgeusia as a result of topiramate therapy is not well identified in the literature but has been reported by patients in online chat forums.7 More frequently identified in the literature as causing carbonation taste alterations is acetazolamide, a carbonic anhydrase inhibitor. How long does Topamax stay in your system. a common cold. For a general overview of Topamax, including details about its uses, see this article. Keep in mind that Topamax may cause mood changes,* including depression. In most cases, side effects from Topamax are temporary. Talk with your doctor about the best way to feed your child if youre taking Topamax. You should not drink alcohol while taking Topamax. I want real experience please not someone posting side effects to the medicine as I've read those already. This medication is also used to prevent migraine headaches and decrease how often you get . If your doctor confirms you had a serious allergic reaction to Topamax, they may have you switch to a different treatment. For full access to this pdf, sign in to an existing account, or purchase an annual subscription. You should not drink alcohol while youre taking Topamax. I was also prescribed it for migraines. Or they may suggest you wean off Topamax and try a different treatment for your condition. 6. For example, fatigue (low energy) and feelings of burning or numbness in your hands and feet may go away as you continue taking Topamax. it totally sucks. Do not break, crush, or chew it. The drug can cause side effects such as sleepiness or diarrhea in a breastfed child. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide, This PDF is available to Subscribers Only. If youve had an allergic reaction to Topamax or any of its ingredients, you should not take Topamax. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Learn about common, mild, and serious side effects it can cause and how, Migraine auras are sensory symptoms, including visual disturbances and physical sensations, that occur during or before a migraine episode. You may need additional blood tests to monitor your levels while youre taking Topamax. You could also download a reminder app on your phone. Weight loss is a common side effect of Topamax. Overall these things don't bother me. The list below may not include all possible serious side effects of the drug. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, burning or numbness in your hands and feet, chronic obstructive pulmonary disease (COPD), North American Antiepileptic Drug Pregnancy Registry, https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/020505s062,020844s053lbl.pdf, One-hour endoscopic procedure could eliminate the need for insulin for type 2 diabetes, New clues to slow aging? However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. However, you should not stop taking Topamax unless your doctor recommends this. I know topamax (topiramate) for migraine also works as appetite suppressant, but what is the chemical reason? Still looking for answers? Its not likely. My sense of taste and smell are coming back and I'm starting to sweat like a normal person again. Try searching for what you seek or ask your own question. When my doctor prescribed Topamax to me I was also in bed crying, we were on Zoom together, so maybe she said something about my taste buds going funky and I don't remember lol. They may suggest medication to manage your symptoms. In studies, this side effect was more common in people who took the drug to treat epilepsy than to prevent migraine headaches. lol, Scan this QR code to download the app now. Symptoms can include: feeling agitated, aggressive, or irritable, losing interest in activities you normally enjoy, Ask the tough question: Are you considering suicide?. In most cases, eye side effects go away if you stop taking the drug. (An active ingredient is what makes a drug work.) These side effects may be temporary, lasting a few days or weeks. Topamax (topiramate) is a prescription drug that's used to treat epilepsy and help prevent migraine headaches. Liver problems. Not to mention it took that long for the word slurring feeling and brain fog to go away. Youll likely take Topamax long term if you and your doctor agree that its working well for you. If you have glaucoma, Topamax may not be safe for you to take. I can't drink sodas anymore because they taste just awful - and milk chocolate tastes bad, but dark chocolate tastes fine. Get answers from Cardiologists and top U.S. doctors, Our doctors evaluate, diagnose, prescribe, order lab tests, and recommend follow-up care. Yes, Topamax may cause sexual side effects, such as decreased sex drive. This is because the drug can cause reduced growth in children. Ok so I drink a crap ton of Coca Cola and for some reason it taste like it has Vodka in it lol. What I learned and what the Dr. Reccomended was take B vitamins every day. If you drink alcohol and have questions about Topamaxs alcohol interaction, talk with your doctor. Topamax is approved to treat certain types of seizures and help prevent migraine headaches. See the Topamax prescribing information for details. Serious side effects that have been reported and their symptoms include: * For more information about this side effect, see Side effect specifics below. Topamax is used to treat epilepsy and to prevent migraine headaches. Yes, its possible to gain weight after stopping Topamax. bruising under the skin. To help make sure that you dont miss a dose, try using a medication reminder. It has been FDA-approved since 1996 for the treatment of epilepsy in both children and adults. Your doctor can help determine whether treatment with Topamax is safe for you if you have liver problems. I was wondering what foods taste different to you since taking Topamax? Topamax can cause certain stomach-related side effects. But taking the drug with food may help lessen any stomach problems you have. Ask if Tenex will work for you. Be sure to talk with your doctor and pharmacist about all of the drugs you take before starting Topamax. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Official answer. Najafizade et al24 demonstrated that zinc supplementation increased perception of all sweet, sour, bitter, and salty tastes among patients with head or neck cancer undergoing radiotherapy. Never disregard or delay professional medical advice in person because of anything on HealthTap.
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